A genetic condition known as 22q.11.2 deletion syndrome is associated with an increased risk of schizophrenia. A Penn Vet-led team found that a leaky blood-brain barrier, allowing inappropriate immune involvement in the central nervous system, may contribute to this or perhaps other neuropsychiatric conditions. Credit: Jorge Iván Alvarez Read Time:
Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP). In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflammation that arise
Blood-brain barrier and its effect on the immune system play a role in schizophrenia
Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP).
In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflammation that arises likely contributes to the clinical manifestations of neuropsychiatric conditions.
The immune link between a leaky blood-brain barrier and schizophrenia upenn.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from upenn.edu Daily Mail and Mail on Sunday newspapers.
Court sinks dream of $1.6bn tourism mecca A Federal Court ban imposed on the director of besieged finance outfit Mayfair 101 effectively leaves in doubt a $1.6bn tourism vision.
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Subscriber only A FEDERAL Court ban imposed on the director of besieged finance outfit Mayfair 101 effectively leaves in doubt a $1.6bn tourism vision for Mission Beach and Dunk Island. On Monday Mayfair 101 founder James Mawhinney was banned from advertising investments and accepting funds from any financial product for 20 years. And assets secured through Mayfair products can t be transferred out of the country. The decision was a final blow to the Mayfair founder following an Australian Securities and Investments Commission move to shut down investment products found by the court to mislead and deceive mum and dad investors lured by the promise of security claimed to be similar to that of a bank.
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IMAGE: A genetic condition known as 22q.11.2 deletion syndrome is associated with an increased risk of schizophrenia. A Penn Vet-led team found that a leaky blood-brain barrier, allowing inappropriate immune involvement. view more
Credit: Courtesy of Jorge Iván Alvarez
Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation at least when all is functioning normally.
That may not be the case in people with schizophrenia and other mental disorders, suggest new findings from a team led by researchers from the School of Veterinary Medicine, Perelman School of Medicine, and Children s Hospital of Philadelphia (CHOP). In these individuals, a more permissive barrier appears to allow the immune system to get improperly involved in the central nervous system, the researchers showed. The inflammation that arises likely contributes to the clinical manifestations of neuropsychi