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Vaccine stockpiling by nations could lead to increase in COVID-19 cases, novel variant emergence
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Fifteen faculty members transfer to emeritus status
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Study solves mystery of how cells measure their size
Scientists have searched for years to understand how cells measure their size. Cell size is critical. It s what regulates cell division in a growing organism. When the microscopic structures double in size, they divide. One cell turns into two. Two cells turn into four. The process repeats until an organism has enough cells. And then it stops. Or at least it is supposed to.
The complete chain of events that causes cell division to stop at the right time is what has confounded scientists. Beyond being a textbook problem, the question relates to serious medical challenges: Cells that stop dividing too soon can cause defects in growing organisms. Uncontrolled cell growth can lead to cancers or other disorders.
Ludwig Cancer Research announced the launch Tuesday of the newest branch of the Ludwig Institute for Cancer Research, which will be based at Princeton University. The Ludwig Princeton branch will be dedicated to the study of cancer metabolism.
Ludwig Princeton will be directed by chemical biologist and cancer researcher Joshua Rabinowitz, a professor in the chemistry department and the Lewis-Sigler Institute for Integrative Genomics at the university. Rabinowitz has made foundational contributions to the field of metabolomics, which is the large-scale, quantitative analysis of metabolite. He is a leader in the development and application of new technologies for the dynamic analysis of metabolic processes. His laboratory has applied this expertise to the dissection of cancer metabolism and is devising candidate cancer therapies based on the lab’s discoveries.
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