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Fármaco para enfermedades psiquiátricas puede evitar cáncer
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Fármaco para enfermedades psiquiátricas puede evitar cáncer
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A biologist working on immunotherapy holds test tubes as he works in the lab (Photo by SAUL LOEB/AFP via Getty Images)
A psychiatric drug available on the NHS could be the key to preventing bowel cancer, scientists say.
Researchers believe lithium can boost the fitness of healthy stem cells in the gut, making them more resistant to sabotage from mutant cells that cause the cancer.
Their findings have led to the launch of a new clinical trial to test if lithium – a commonly used drug for the treatment of several psychiatric disorders – could be used to prevent the development of bowel cancer.
The study, published in the journal
Nature, shows how a drug available on the NHS can boost fitness of healthy stem cells in the gut, making them more resistant to sabotage from mutant stem cells that cause cancer.
Researchers in the Netherlands, funded by the UK charity Worldwide Cancer Research, have discovered a way to boost the fitness of healthy cells in the gut to prevent the development of bowel cancer. The findings have led to the initiation of a clinical trial to find out if a commonly used psychiatric drug could be used to prevent bowel cancer in people. The trial will recruit patients with a genetic mutation that means they are virtually 100% certain to develop bowel cancer in their lifetime, unless the entire large bowel is removed.
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