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Reportable, Inc.: Pacylex Pharmaceuticals Closes Series A Funding to Advance Oncology Program into the Clinic

Reportable, Inc.: Health Canada Clears Pacylex Pharmaceuticals for New Phase 1 Clinical Trial to Evaluate PCLX-001 Capsules in the Treatment of Hematologic and Solid Tumor Cancers

Reportable, Inc.: Health Canada Clears Pacylex Pharmaceuticals for New Phase 1 Clinical Trial to Evaluate PCLX-001 Capsules in the Treatment of Hematologic and Solid Tumor Cancers Key Takeaways: Scientists at the University of Alberta have recently published evidence that a new drug could work in blood cancers by targeting B-cell signaling. Scientists at the University of Alberta also published a study showing potential in breast cancer. PCLX-001 led to significant tumor regression in mouse models, including completely eliminating lymphoma tumors derived from a patient whose cancer had stopped responding to the standard therapies CHOP and Roche s Rituxan. Click image above to view full announcement.

New drug target valid for breast cancer as well as lymphoma

New drug target valid for breast cancer as well as lymphoma One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research. The results provide more justification and rationale for starting the clinical trial in May. It s another exciting stepping stone to finding out if this is going to be a new cancer treatment. John Mackey, First Author, Professor and Director of Oncology Clinical Trials, Faculty of Medicine & Dentistry, University of Alberta The drug PCLX-001 is designed to selectively kill cancer cells by targeting enzymes involved in myristoylation, a process key to the cell signaling system that is often defective in cancer cells. The molecule was originally developed by the University of Dundee as a treatment for African sleeping sickness. U of A cell biologist Luc Berthiaume was the first to realize it could work aga

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