Role of Lipids in Cancer
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Research has shown that the establishment of tumorous cells, as well as their rapid proliferation, are supported by the synthesis or increased uptake of lipids. The altered lipid metabolism influences different stages of the disease, which we discuss below.
Lipid metabolism in cancer
Tumors require substantial and reliable sources of energy to feed their uncontrolled, abnormal cell growth. Usually, cells hydrolyze glucose via the process of glycolysis to obtain a source of adenosine triphosphate (ATP), which provides energy for the cell. This process is an aerobic reaction, requiring a supply of oxygen.