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Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.
While drugs and mosquito control have reduced levels of malaria over recent decades, the parasite still kills over 400,000 people every year, infecting many more. Worryingly, it has now developed resistance to many existing antimalarial drugs, meaning new treatments that work in different ways are urgently needed.
In their research, published in
PNAS, the scientists developed a set of compounds designed to stop the parasite being able to burst out of red blood cells, a process vital to its replication and life cycle. They found one compound in particular was highly effective in human cell tests.
New drug-like compound could effectively block a critical step in malaria parasite life cycle
Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.
While drugs and mosquito control have reduced levels of malaria over recent decades, the parasite still kills over 400,000 people every year, infecting many more. Worryingly, it has now developed resistance to many existing antimalarial drugs, meaning new treatments that work in different ways are urgently needed.
ISE 2021 roadshow in disarray as events cancelled
ISE 2021 roadshow in disarray as events cancelled
posted on Friday, 30th April 2021 by Steve May
Plans for a series of local ISE roadshows to replace this yearâs Barcelona ISE trade show have already started to unravel in the face of ongoing COVID restrictions.
In a statement today, Mike Blackman, Managing Director Integrated Systems Events, announced the cancellation of planned Munich and Amserdam events.
Blackman said: âWe have today made the decision to cancel the ISE events planned for Munich and Amsterdam. Whilst we have had good support from both exhibitors and visitors who wanted to get together at a local event, new government regulations regarding COVID-19 in both Germany and the Netherlands have meant that we are unable to guarantee being able to proceed with these two events.
Barcelona looks forward to welcoming ISE Live and Online Spain – Integrated Systems Events’ Managing Director, Mike Blackman, has returned to Barcelona this week (13-16 April) as the city prepares to welcome ISE Live and Online.
Mike Blackman was taking part in the Barcelona reACT Conference, a four-day working event to relaunch the city’s economy after a year of pandemic. Speaking at the conference and looking forward to June, Blackman said: “We recognise that the world needs events to get back to business and we are thankful for the support we have had from the national, regional and City authorities, the team at the Fira and of course to the pro AV industry for its enthusiasm in the face of what has been an incredibly difficult period. Whilst 2021 will offer a different experience we are confident of delivering a great event which will pave the way for ISE 2022 in Barcelona.”
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