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email article Compared with white peers, Black youth under the age of 13 have double the rate of suicide. On top of that, the rate of Black youth who contemplated suicide rose in the past decade from 12.95% to 16.89%. Applying the white-centric lens that has driven existing suicide research is not sufficient to solving the increasing rates of suicide among Black youth, wrote Arielle Sheftall, PhD, of Nationwide Children s Hospital in Columbus, Ohio, in a statement. ( JAMA Pediatrics) CVL-231, a novel muscarinic M4-selective positive allosteric modulator, succeeded in a phase Ib trial of adults with schizophrenia. A dose of 30 mg once daily improved Positive and Negative Syndrome Scale (PANSS) total score by 12.7% by week 6 versus placebo, with no safety issues, Cerevel Therapeutics announced.

New yorkUnited statesNew zealandUnited kingdomArielle sheftallThomas laughrenUniversity of maryland children hospitalNeurological instituteOhio state university wexner medical centerNationwide childrenNegative syndrome scaleCerevel therapeuticsClinical psychiatryDentalslim dietBritish dentalMaryland children