New assay using fresh uncultured lung tumor cells could guide personalized treatments news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
Share
In March of 2020, thousands of scientists around the world united to answer a pressing and complex question: what genetic factors influence why some COVID-19 patients develop severe, life-threatening disease requiring hospitalization, while others escape with mild symptoms or none at all?
A comprehensive summary of their findings to date, published in Nature, reveals 13 loci, or locations in the human genome, that are strongly associated with infection or severe COVID-19. The researchers also identified causal factors such as smoking and high body mass index. These results come from one of the largest genome-wide association studies ever performed, which includes nearly 50,000 COVID-19 patients and two million uninfected controls.
GWAS Reveals Multiple Host Genes Linked to Severe COVID-19 Symptoms
July 9, 2021
A global initiative founded in March 2020 called the COVID-19 Host Genomics Initiative has released a comprehensive summary of their findings, which reveal 13 loci in the human genome that are strongly associated with infection or severe COVID-19. The researchers also identified causal factors such as smoking and high body mass index. The results, published in
Nature, come from one of the largest genome-wide association studies (GWAS) ever performed, which includes nearly 50,000 COVID-19 patients and two million uninfected controls. The findings could help provide targets for future therapies and illustrate the power of genetic studies in learning more about infectious disease.
Genetic flashpoints: Why Covid-19 hits some people harder than others
SECTIONS
Last Updated: Jul 10, 2021, 10:54 AM IST
Share
Synopsis
The Nature report summarizes information from 46 studies and three meta-analyses investigating the role of human genetics in Sars-CoV-2 infections and Covid-19 severity.
ANI
Throughout the pandemic, one crucial question has perplexed scientists worldwide: Why do some people become so sick from Covid-19 while others show no symptoms at all?
Now, a peek deep into the human genome by a global initiative with more than 3,000 researchers from 25 countries is providing some answers. There are 13 locations in the genome strongly linked to either susceptibility to the virus or severe cases, the researchers reported Thursday in the journal Nature.
Qatar Foundation researchers participate in global genomic studies on COVID-19 patients thepeninsulaqatar.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thepeninsulaqatar.com Daily Mail and Mail on Sunday newspapers.