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Emory University is participating in a study evaluating immune responses to COVID-19 vaccines, when the vaccines are administered during pregnancy or within two months after delivery.
The study, called SARS-CoV-2 Vaccines in Pregnancy and Postpartum or MOMI-Vax, is sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. MOMI-Vax is being conducted by the NIAID-funded Infectious Diseases Clinical Research Consortium (IDCRC).
MOMI-Vax is open to people who have received any of the FDA-authorized COVID-19 vaccines. The early COVID-19 vaccine clinical trials generally excluded pregnant women, so there is limited data on immune responses for this special population. However, after the FDA authorized the vaccines, regulators gave people who were pregnant or soon to be pregnant the option of choosing to get the vaccines. Tens of thousands of pregnant and breastfeeding people across the country have b
While the amount of antibodies transferred was less than expected, Emory researchers call the evidence reassuring. Author: Liza Lucas Updated: 7:29 AM EST February 2, 2021
ATLANTA A new study may provide some much-needed reassurance for women who are pregnant during the pandemic.
The study, conducted by researchers at Emory University School of Medicine, found evidence that COVID-19 antibodies can indeed transfer from mom to baby. It s scary to be pregnant during the coronavirus pandemic, Dr. Martina Badell, an associate professor in the Department of Gynecology & Obstetrics, told 11Alive. We started a protocol at Emory after the virus hit to study the immune response to COVID-19 infection in pregnancy.
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Editor s Note: This story was updated at 4:00 pm CST, adding in the second, unpublished, study.
SARS-CoV-2 antibodies transferred across the placenta in 87% of pregnant women who had COVID-19 at some point, suggesting that newborns of seropositive mothers may have some protection against the novel coronavirus at birth, according to a study today in
JAMA Pediatrics. However, a second, unpublished study suggests that the maternal-infant antibody transfer is lower than expected.
IgG but not IgM in cord blood
In the first study, a team led by researchers from Children s Hospital of Philadelphia collected discarded maternal and cord blood sera from 1,471 mother-newborn pairs with available sera for measurement of anti-spike protein immunoglobulin G (IgG) and immunoglobulin M (IgM) at Pennsylvania Hospital from Apr 9 to Aug 8.