Novartis reaches milestone delivery of 1 billion courses of 3blmedia.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from 3blmedia.com Daily Mail and Mail on Sunday newspapers.
3 May 2021
Results from the Oxford Jenner Institute trial of a malaria vaccine give it a 77% success rate. In a 2012 article detailing the many attempts to combat the disease, which kills more than 400,000 people a year, Pauline Léna commented that ‘the battle is as political as scientific. (.) While we await a technological solution, the efforts of governments and donors to improve access to treatment and the means of prevention remain the most effective weapon against this pandemic.’
Ten-year fight for world health
Malaria, the year of hope
Each minute, a child dies of malaria. Yet medicines exist. And a vaccine may come soon
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A Wyss Institute-led collaboration spanning four research labs and hundreds of miles has used the Institute s organ-on-a-chip (Organ Chip) technology to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes COVID-19.
The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the process of evaluating the safety and efficacy of existing drugs for new medical applications, and provides a proof-of-concept for the use of Organ Chips to rapidly repurpose existing drugs for new medical applications, including future pandemics. The research is reported in
Nature Biomedical Engineering.
While many groups around the world have been testing existing drugs for efficacy against COVID-19 using cultured cells, it is well known that cells grown in a dish do not behave like the cells in a living human body, and many drugs that appear effective in lab studies do not work in patients. T
Largest clinical trial in Africa for people with mild COVID-19 to test new treatment eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Drug-discovery collaboration finds potential new antimalarial drug candidates
Potential new antimalarial drug candidates are being developed through an extended drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation.
A collaborative research team discovered compounds with antimalarial activity within a collection of 80,000 drug-like molecules in the Janssen Jump-stARter Compound Library, a unique collection of drug-like compounds designed to fast track the discovery of new medicines. Under the agreement, the most promising candidates are now being further developed by the researchers towards potential antimalarial drugs, which could lead to powerful new weapons in the global fight against this disease.