Study reveals how ecDNA forms, drives cancer drug resistance ANI | Updated: Dec 24, 2020 11:54 IST
Washington [US], December 24 (ANI): Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.
The research, published in the journal Nature, provides new insights into how cancers evolve to adapt to changing environments and suggests ways to reduce drug resistance by combining therapies. Drug resistance is the most problematic part of cancer therapy. If not for drug resistance, many cancer patients would survive, said Ofer Shoshani, a postdoctoral researcher in Cleveland s lab and the study s first author.
USAID holds child-friendly community TB screening in Dinalupihan bignewsnetwork.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bignewsnetwork.com Daily Mail and Mail on Sunday newspapers.
DRUG RESISTANT TB NEXT BIG HEALTH THREAT IN Submitted by admin on Thu, 08/05/2010 - 00:00
PNG
Major effort urged to stem tide
PORT MORESBY, Papua New Guinea (PNG Post-Courier, Aug. 5, 2010) – PAPUA New Guinea’s gains in tuberculosis (TB) control over the last decade would be lost unless multidrug-resistant and extensively drug-resistant TB, as well as TB-HIV co-infection are urgently addressed, the World Health Organisation (WHO) has warned.
WHO says countries in the region, including PNG had made huge progress towards the regional goal of decreasing by half TB prevalence and mortality rates compared to 2000 levels. These successes may be reversed unless gaps in financial and technical support are put in place to effectively address these challenges, Dr Shin Young-soo, WHO Regional Director for the Western Pacific said last week.