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Biden s Top Science Nominee Advocated Preimplantation Genetic Testing to Decide Which Human Embryo to Keep

Biden s Top Science Nominee Advocated Preimplantation Genetic Testing to Decide Which Human Embryo to Keep
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Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene Editing Hold Potential to Correct Retinal Degenerations

Gene Editing Hold Potential to Correct Retinal Degenerations by Angela Mohan on  January 20, 2021 at 11:44 AM Gene editing therapies, including CRISPR-Cas systems hold promise in correcting mutations that are responsible for inherited retinal degenerations. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges are highlighted in the peer-reviewed journal Human Gene Therapy. Currently, the field is undergoing rapid development with a number of competing gene editing strategies, including allele-specific knock-down, base editing, prime editing, and RNA editing, are under investigation. Each offers a different balance of on-target editing efficiency versus off-target risks, state Kanmin Xue, University of Oxford, and coauthors.

Genome editing to treat human retinal degeneration

 E-Mail IMAGE: Provides all-inclusive access to the critical pillars of human gene therapy: research, methods, and clinical applications. view more  Credit: Mary Ann Liebert, Inc., publishers New Rochelle, NY, January 19, 2021 Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges are highlighted in the peer-reviewed journal Human Gene Therapy. Click here to read the full-text article free on the Human Gene Therapy website. Currently, the field is undergoing rapid development with a number of competing gene editing strategies, including allele-specific knock-down, base editing, prime editing, and RNA editing, are under investigation. Each offers a different balance of on-target editing efficiency versus off-target risks, state Kanmin Xue, Unive

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