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Pharmaxis Ltd has multiple potential value inflection points with two drugs advancing in clinical trials

Pharmaxis Ltd (ASX:PXS) (FRA:UUD) has multiple potential value inflection points over the next two years, with two drugs in clinical trials that are due to report meaningful efficacy and safety endpoints in patients by the end of 2022.  The company has a platform technology that has delivered a pipeline of first in class or best in class clinical drugs for inflammatory and fibrotic diseases. The first of these drugs already has an IND approval from the FDA and is currently being trialled in myelofibrosis patients. Its lead asset PXS-5505 – with disease-modifying potential in myelofibrosis – is in Phase 1c/2 trial, with further collaborations to extend the value of PXS-5505 in a variety of other oncology indications where there is strong unmet need.

World-first trial for Australian company Pharmaxis

(ASX:PSX) has announced a partnership to launch a world-first clinical trial that aims to stop scars from forming after trauma, particularly following burn injuries. The company is partnering with distinguished surgeon and burns expert Professor Fiona Wood AM who is leading a group of researchers from the University of Western Australia (UWA) and Fiona Stanley Hospital to test a treatment in the first human trials. Pharmaxis said its discovery, known as PXS‐6302, has shown promising pre‐clinical results in inhibiting the enzymes that play a critical role in the development of scar tissue. PXS‐6302 was discovered by the company’s researchers at its laboratories in Sydney.

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