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SEATTLE, March 10, 2021 /PRNewswire/ Principal Investigator Oliver Harrison, DPhil, at the Benaroya Research Institute at Virginia Mason (BRI) has been awarded a $2.9 million-dollar 5-year Research Project Grant (R01) by the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to study the mechanisms by which the immune system responds to the body s microbiome, and how these immune responses go awry during inflammatory, immune-mediated and autoimmune disorders.
The study has a particular focus on ways to prevent skin infection while accelerating wound repair through manipulation of microbiome-specific T-cells found within the skin. Better understanding of these T-cell responses and how they are regulated can potentially lead to new therapies for inflammatory disorders such as psoriasis, the most prevalent autoimmune disease in the United States, and inflammatory bowel disease, which has bee