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Shikimic Acid in Giant Sequoia Converts Fibroblasts, Regenerates Skin July 6, 2021 Contact Author Rachel Grabenhofer Close Sponsored Sequoiadendron giganteum (giant sequoia, GS) callus extract, can reprogram dermal fibroblasts.  According to the article abstract, a team of researchers from Seoul National University Hospital, SK Chemical, AmorePacific, Chung-Ang University College of Medicine and Pusan National University School of Medicine hypothesized a component from plant stem cells could convert human fibroblasts to skin-derived percursors (SKPs). The latter are reportedly good for skin regeneration but their isolation from skin is limited. Here, the team treated human dermal fibroblasts with GS callus extract, of which shikimic acid is a major component. The acid induced nestin expression, fibronectin and vimentin and the fibroblasts could differentiate. Subsequently, it was confirmed to facilitate wound healing and enhance dermal reconstruction in a human

Soult ukpyolsiSouth koreaSeoul national university hospitalChung ang university college of medicineStem cell research therapyPusan national university school of medicineStem cell researchChung ang university collegePusan national university schoolதெற்கு கொரியாசியோல் தேசிய பல்கலைக்கழகம் மருத்துவமனைசுங் அங் பல்கலைக்கழகம் கல்லூரி ஆஃப் மருந்துதண்டு செல் ஆராய்ச்சி சிகிச்சைபுசன் தேசிய பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்துதண்டு செல் ஆராய்ச்சிசுங் அங் பல்கலைக்கழகம் கல்லூரி