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AavantiBio Bolsters Leadership Team with Appointment of Ty Howton as Chief Operating Officer and General Counsel

AavantiBio Bolsters Leadership Team with Appointment of Ty Howton as Chief Operating Officer and General Counsel
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Provention Bio Announces Key Findings from Pre-clinical Proof-of-concept Study for PRV-3279 for the Prevention of Immunogenicity of Gene Therapy

Share this article Share this article RED BANK, N.J., Jan. 28, 2021 /PRNewswire/  Provention Bio, Inc. (Nasdaq: PRVB), a biopharmaceutical company dedicated to intercepting and preventing immune-mediated diseases, today reported results from a pre-clinical proof-of-concept study for PRV-3279, a DART® (bispecific antibody-based molecule) targeting the B cell surface proteins CD32B and CD79B, conducted in a murine model of gene therapy for Pompe disease. A PRV-3279 mouse surrogate was tested in mice transgenic for human CD32B, which received gene therapy with an adeno-associated virus (AAV) vector AAV9 encoding for the enzyme acid-alpha-glucosidase (GAA) gene.  Errors in the GAA gene cause the serious human glycogen storage disease type II (Pompe disease).

Auburn COSAM alum dedicated to curing diseases with new gene therapy venture

Auburn COSAM alum dedicated to curing diseases with new gene therapy venture Published: January 14, 2021 Decrease Font Size Font Size Increase Font Size Article body Auburn alum Bo Cumbo is dedicated to saving the world – by defeating one rare disease at a time. The 1994 laboratory technology graduate is busy building his newest gene therapy venture, AavantiBio, as he puts more than a quarter century of experience to work fighting rare or specialty diseases. Buoyed by $107 million in funding from private investors, industry leaders and former employers, Cumbo is unleashing AavantiBio on several of the more than 7,000 rare diseases he says are still without a cure.

Irish Sailing Fixtures for 2021? The Best Plan is to Keep Planning

19th December 2020 The National YC s biennial Volvo Dun Laoghaire to Dingle Race, currently scheduled for June 9th 2021, could become symbolic of the emergence from pandemic. The start of 2019 s race shows overall winner Paul O Higgin s JPK 10.80 Rockabill VI (left) showing briefly ahead of Mick Cotter s 94ft line honours winner and new course record-setter Windfall Credit: Afloat.ie/David O Brien In normal times, the yearly Irish sailing fixtures list is a reasonably harmonious programme based around annual or biennial pillar events of various types and sizes, an ongoing succession of regattas and championships which slot together in a reasonably meaningful structure which is dictated by traditional times of the year, and the needs of the bigger one design classes – particularly the dinghies – to find a location which will accommodate them for their annual national championship.

Muscular Dystrophy Association Releases FAQs for the Neuromuscular Disease Community for Access to the COVID-19 Vaccines

Muscular Dystrophy Association Releases FAQs for the Neuromuscular Disease Community for Access to the COVID-19 Vaccines
idahostatejournal.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from idahostatejournal.com Daily Mail and Mail on Sunday newspapers.

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