King’s College London
The new marker could improve the quality of life for patients
Researchers from the School of Biomedical Engineering & Imaging Sciences proposed a new metric, curvature of the left ventricular endocarium to characterise anatomical changes in the left ventricle related to high blood pressure in early stages of the disease. The new marker helps clinicians choose the most effective drugs, which can stop or reverse the changes in cardiac morphology, improving the working of the heart and patient quality of life.
The research published in the Journal of Hypertension investigates what is known as basal septal hypertrophy (BSH) a local thickening of the upper interventricular septum (the partition between the left and right ventricle) and constitutes a marker of an undesirable anatomical changes in patients with hypertension. Aside from the increased risk of cardiac events and weaker cardiac function having the BSH may impact the quality of life, cause shortness of
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MRI scanning can more precisely define and detect head, neck, thoracic, abdominal and spinal malformations in unborn babies, finds a large multidisciplinary study led by King s College London with Evelina London Children s Hospital, Great Ormond Street Hospital and UCL.
In the study, published today in
Lancet Child and Adolescent Health, the team of researchers and clinicians demonstrate the ways that MRI scanning can show malformations in great detail, including their effect on surrounding structures. Importantly, they note that MRI is a very safe procedure for pregnant women and their babies.
They say the work is invaluable both to clinicians caring for babies before they are born and for teams planning care of the baby after delivery.
An open-source platform, OpenEP co-developed by researchers from the School of Biomedical Engineering & Imaging Sciences at King's College London has been made available to advance research on atrial fibrillation, a condition characterized by an irregular and often fast heartbeat.