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Latin American and Caribbean research contributions to tackle challenges posed by brain diseases Every year there are nearly ten million new cases of dementia globally, of which Alzheimer s Disease (AD) is the most common form, accounting for around 60-70% of cases. This special supplement, published in the Journal of Alzheimer s Disease, focuses on the challenges posed by brain disease and presents significant research contributions from Latin America and the Caribbean that address these challenges to help improve the lives of individuals with AD. AD is a complex, multifactorial neurodegenerative disorder that represents a major and increasing global health challenge. Neuroscience is making strides in unraveling the brain s secrets through translational research and drug discovery in order to improve the lives of individuals with a wide variety of neurological and psychiatric disorders such as AD, Parkinson s disease, schizophrenia, depression, traumatic brain injury, epilepsy,

United statesMexico cityDistrito federalAlta tecnologGabrielle brittonCarold sanmartEmily hendersonFarmaciay bioquCarlos velez pardoLuisa rochaKs jagannatha raoNeuroscience research groupUniversity of chileSchool of biotechnologyDepartment of pharmacobiologyDepartment of neurology