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Researchers use new way to detect high-risk Human Papilloma Virus

Researchers use new way to detect high-risk Human Papilloma Virus A study led by Queen Mary University of London researchers has compared the performance and acceptability of a urine test and four different vaginal self-sampling collection devices to detect high risk Human Papilloma Virus (HPV). Uptake of cervical screening has been declining in the UK in recent years, and self-sampling is an attractive alternative to clinician collected samples, initially in non-attenders but potentially for all women as the primary option. Jack Cuzick, Study Corresponding Author and Professor, Queen Mary University of London Related Stories Cost and simplicity of use are important factors, and in low- and middle-income countries self-sampling may prove to be the only practical cost-effective option. High performance and acceptability of self-sampling is essential if this is to become the first option. Understanding preferences for a urine rather than a vaginal sample is important, and perhap

Evaluating HPV self-sampling

 E-Mail A study led by Queen Mary University of London researchers has compared the performance and acceptability of a urine test and four different vaginal self-sampling collection devices to detect high risk Human Papilloma Virus (HPV). Corresponding author Professor Jack Cuzick from Queen Mary University of London said: Uptake of cervical screening has been declining in the UK in recent years, and self-sampling is an attractive alternative to clinician collected samples, initially in non-attenders but potentially for all women as the primary option. Cost and simplicity of use are important factors, and in low- and middle-income countries self-sampling may prove to be the only practical cost-effective option. High performance and acceptability of self-sampling is essential if this is to become the first option. Understanding preferences for a urine rather than a vaginal sample is important, and perhaps a choice should be offered.

More accurate method to predict long term outcomes for pre-invasive breast cancer

 E-Mail A study by Queen Mary University of London researchers, funded by Cancer Research UK, confirms the role of the oestrogen receptor biomarker in ductal carcinoma in situ and presents a new and more accurate method to predict long term outcomes for this pre-invasive stage of breast cancer. The study is published in Clinical Cancer Research. Oestrogen receptor (ER), a protein expressed in some breast cancer cells, is routinely tested in invasive breast cancer to predict long-term outcomes select treatment options. Its role in ductal carcinoma in situ (DCIS) has been previously unclear, and it is not generally evaluated in this pre-invasive stage of breast cancer. The new research confirms the role of ER in predicting long-term outcomes in DCIS, and the authors report a new and more accurate method to evaluate ER for predicting long-term outcomes in DCIS.

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