The crash happened at the intersection of Palm Road and Chatham Road.
The school bus was empty, confirmed Ball-Chatham School District spokeswoman Betsy Schroeder.
The woman had to be extricated from her SUV by Chatham Fire personnel. Three other occupants of the SUV, all juveniles, were treated and released.
The woman was issued a citation for driving while her license was suspended and a citation for failure to reduce speed.
It was not immediately clear if weather played a factor.
Schroeder said the bus was being test driven after repair by a mechanic who is employed by the school district. He was the lone occupant and uninjured.