Left Atrial Appendage Occlusion, DOAC Comparable for AFib medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.
January 08, 2021
High-risk patients with atrial fibrillation may have better outcomes with left atrial appendage (LAA) closure with the Amplatzer Amulet device (Abbott) than with direct oral anticoagulant (DOAC) treatment, an observational analysis suggests.
The rate of ischemic stroke through 2 years of follow-up was similarly low in the two groups, although LAA closure was associated with lower rates of major bleeding and both all-cause and CV mortality, lead author Jens Erik Nielsen-Kudsk, MD, DMSc (Aarhus University Hospital, Denmark), and colleagues report.
They note, however, that interpretation of the study, published in the January 11, 2021, issue of
JACC: Cardiovascular Interventions, “is limited by the observational design, and the results need confirmation in randomized clinical trials.”