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This new research was prospectively gathered in Denmark and involved nationwide, population-based data as well as a uniform approach to melanoma treatment and surveillance.
Denmark has experienced a remarkable reduction in CVD mortality over recent decades. The scale of the health contribution from the Danish regulation on industrially produced trans fatty acid (ITFA) has therefore long been of interest. Thus the objective was to determine health and equity benefits of the Danish regulation on ITFA content in Danish food, by quantifying the relative contributions of changes in ITFA intake, other risk factors and treatments on coronary heart disease (CHD) mortality decline from 1991 to 2007 in Denmark, stratified by socioeconomic group. To evaluate the effects of the ITFA ban (Danish Order no. 160 of March 2003) the Danish IMPACTSEC model was extended to quantify reductions in CHD deaths attributable to changes in ITFA (%E) intake between 1991–2007. Population counts were obtained from the Danish Central Office of Civil Registration, financial income from Statistics Denmark and ITFA intake from Dan-MONICA III (1991) and DANSDA (2005–2008). Part
Left Atrial Appendage Occlusion, DOAC Comparable for AFib medscape.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medscape.com Daily Mail and Mail on Sunday newspapers.
January 08, 2021
High-risk patients with atrial fibrillation may have better outcomes with left atrial appendage (LAA) closure with the Amplatzer Amulet device (Abbott) than with direct oral anticoagulant (DOAC) treatment, an observational analysis suggests.
The rate of ischemic stroke through 2 years of follow-up was similarly low in the two groups, although LAA closure was associated with lower rates of major bleeding and both all-cause and CV mortality, lead author Jens Erik Nielsen-Kudsk, MD, DMSc (Aarhus University Hospital, Denmark), and colleagues report.
They note, however, that interpretation of the study, published in the January 11, 2021, issue of
JACC: Cardiovascular Interventions, “is limited by the observational design, and the results need confirmation in randomized clinical trials.”