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The FINANCIAL - Causal Blood Pressure Genes Found in the Human Kidney

Share This The FINANCIAL An international team of scientists led by The University of Manchester have discovered 179 kidney genes responsible for high blood pressure. High blood pressure, known as “silent killer”, is one of the most common human diseases and remains the key risk factor for strokes and heart attacks. According to The University of Manchester, high blood pressure - or hypertension- runs in families but the exact mechanisms through which genes influence individuals’ predisposition to hypertension is not clear. The discoveries published in Nature Genetics, one of the world’s leading journals, shed new light on our understanding of genetic predisposition to high blood pressure.

New glowing probe may detect early cardiovascular disease

New glowing probe may detect early cardiovascular disease Researchers have created a probe that glows when it detects an enzyme associated with issues that can lead to blood clots and strokes. The team of researchers, from the Department of Chemistry and the National Lung and Heart Institute at Imperial College London, demonstrated that their probe quickly and accurately detects the enzyme in modified E. Coli cells. They are now expanding this proof-of-concept study, published in the Journal of the American Chemical Society and funded by the British Heart Foundation (BHF), with the hope of creating rapid tests for cardiovascular problems and a new way to track long-term conditions.

Scientists identify kidney genes that appear to directly affect blood pressure | Wilts and Gloucestershire Standard

Researchers have discovered 179 kidney genes that may be responsible for high blood pressure, potentially leading to new strategies for treating the condition. Known as the silent killer, high blood pressure is one of the most common diseases and remains the key risk factor for strokes and heart attacks. The condition – also known as hypertension – runs in families, but the exact mechanisms through which genes influence a person’s predisposition to hypertension is not clear. The findings published in Nature Genetics shed new light on the understanding of this. Researchers, led by Professor Maciej Tomaszewski at the University of Manchester, characterised how information inherited in DNA translates into genetic predisposition to high blood pressure through changes in activity of certain kidney genes.

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