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Using Stimuli-Responsive Biomaterials to Understand Heart Development, Disease Striving for creation of a synthetic platform to mimic natural progression of heart development Shape memory polymer: from flat to nanowrinkles to promote cardiomyocyte alignment Newswise WASHINGTON, March 2, 2021 Cardiovascular disease remains the number one cause of death globally. Unfortunately, the heart cannot regenerate new tissue, because the cardiomyocytes, or heart muscle cells, do not divide after birth. In their paper, published in APL Bioengineering by AIP Publishing, Syracuse researchers developed a shape memory polymer to grow cardiomyocytes. Raising the material’s temperature from 30 degrees Celsius to 37 degrees Celsius turned the polymer’s flat surface into nanowrinkles, which promoted cardiomyocyte alignment.

United statesZhen maChenyan wangHuaiyu shiMechanobiology cardiomyocytes cardiac tissue cardiovascular bioengineering stimuli responsive biomaterials microenvironment heart development disease huaiyu shi chenyan wang zhen ma syracuse universityAll journal newsCardiovascular healthHeart diseaseEmbargoed feed hiddenAmerican institute of physics aipஒன்றுபட்டது மாநிலங்களில்ஜென் மாஅனைத்தும் இதழ் செய்திஇருதய ஆரோக்கியம்இதயம் நோய்அமெரிக்கன் நிறுவனம் ஆஃப் இயற்பியல் ஐபி