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Many bacteria are capable of swimming 60 or even 100 times their own length in a second. This mobility constantly outdistances the cheetah the fastest animal on the planet. Since Van Leeuwenhoek, known as the Father of Microbiology, first observed mobile bacteria in the 17th century, bacterial mobility and their mechanisms have attracted extensive research interests. A host of microbiologists, biochemists and biophysicists have committed their studies in this field, but many questions remain elusive.
Recently, TAN Jiaxing et al. from the Zhejiang University Life Sciences Institute and School of Medicine determined an atomic-resolution cryo-electron microscopy (cryo-EM) structure of the bacterial flagellar motor-hook complex in the assembled state from Salmonella Typhimurium. This study provides detailed molecular insights into the structure, assembly, and torque transmission mechanisms of the flagellar motor. It unravels the mystery of bacterial swimming and swarming mobility
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