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Understanding the dynamics of brain blood flow could hold key for treating neurologic conditions While the human brain has over 400 miles of total vasculature, little is known about the tiny capillaries that make up much of this intricate labyrinth of blood vessels critical for delivering oxygenated blood and nutrients to billions of brain cells. According to Dr. Andy Shih, a principal investigator in the Center for Developmental Biology and Regenerative Medicine at Seattle Children s Research Institute, understanding how this vast network regulates blood flow in the brain could hold the key to new treatments for neonatal and childhood neurologic conditions, such as stroke and hypoxia, and issues of aging like dementia and Alzheimer s disease.

David hartmannAndy shihAndree anne berthiaumeEmily hendersonRegenerative medicine at seattle children research instituteSeattle children research instituteStanford universityDevelopmental biologyRegenerative medicineSeattle childrenResearch instituteStudy principal investigatorNature neuroscienceJuliane gustAlzheimer 39s diseaseBlood vessels