Interaction between LDL cholesterol and PRS can predict risk of heart attack
Allelica, a leading genomics software company specializing in developing polygenic risk scores (PRS) for personalized medicine, today announced publication of a study in
Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person s risk of having a heart attack depends on their genes.
Using Allelica s proprietary PRS analysis software, the data showed that combining information on an individual s genetic risk of heart attack with their LDL level helps determine those at most risk from heart attack, including those potentially in need of treatment with statins or PCSK9 inhibitors.
Apoptosis is an important mediator of pathogenesis in animal coronavirus infection
Apoptosis is a form of programmed cell death, which occurs in cells that are irreparably damaged or in cells infected by some viruses. This mechanism is extremely important in limiting a virus’s replication and its spread to other neighboring cells.
A new paper in the journal
Lifepresents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.
Colorized scanning electron micrograph of an apoptotic cell (blue) infected with SARS-COV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Image Credit: NIAID / Flickr
New research by a team of scientists at University Hospital RWTH Aachen in Germany and Erasmus Medical Centre in The Netherlands characterized changes in CD8+ T cells in response to SARS-CoV-2.
She was imprisoned for killing her four children. But was it their genes all along?
12 Mar, 2021 08:12 PM
7 minutes to read
Kathleen Folbigg with her baby daughter Sarah. She has maintained that her four children died of Sudden Infant Death Syndrome. Photo / Supplied
Kathleen Folbigg with her baby daughter Sarah. She has maintained that her four children died of Sudden Infant Death Syndrome. Photo / Supplied
New York Times
By: Damien Cave
The case of Kathleen Folbigg has become a contest between cutting-edge science and an Australian court system that sometimes ignores it. The tabloids in Australia called Kathleen Folbigg a murderer of innocent babies the