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Allelica Raises $1 75 Million in Seed Financing to Advance Polygenic Risk Score (PRS) Analysis into Clinical Practice

(1) PRS stratifies disease risk and brings precision medicine into clinical routine Allelica, a leading genomics software company specialising in developing polygenic risk scores (PRSs) for common diseases, today announced that the company has raised $1.75 million in a seed financing round led by Valor Ventures, Sternberg Health, Pi Campus, as well as strategic business angels also participated in the round. As part of the transaction, Valor Ventures General Partner Gary Peat has joined the Allelica board of directors and Allelica has relocated its headquarters to New York City. The proceeds of the financing will be used to advance clinical integration of Allelica s PRS software into healthcare systems in the US. A PRS is a measurement of a person s risk of disease based on their genes and is based on combining the effects of a large number of genetic variants across the genome. This information can be used to stratify individuals based on their risk of disease. By combining PRS

Allelica s polygenic risk score data published in i Circulation /i

Allelica s polygenic risk score data published in Circulation Halsin Partners  E-Mail Rome, Italy, March 8, 2021 - Allelica, a leading genomics software company specialising in developing polygenic risk scores (PRS) for personalised medicine, today announced publication of a study in Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person s risk of having a heart attack depends on their genes. Using Allelica s proprietary PRS analysis software, the data showed that combining information on an individual s genetic risk of heart attack with their LDL level helps determine those at most risk from heart attack, including those potentially in need of treatment with statins or PCSK9 inhibitors. The PRS was also able to identify individuals eligible for therapeutic intervention based on current guidelines, which do not include polygenic risk, but who are in fact at low risk of heart attack based on their genes and LDL levels, so co

Allelica s polygenic risk score data published in Circulation

Allelica s polygenic risk score data published in Circulation
sciencecodex.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencecodex.com Daily Mail and Mail on Sunday newspapers.

Interaction between LDL cholesterol and PRS can predict risk of heart attack

Interaction between LDL cholesterol and PRS can predict risk of heart attack Allelica, a leading genomics software company specializing in developing polygenic risk scores (PRS) for personalized medicine, today announced publication of a study in Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person s risk of having a heart attack depends on their genes. Using Allelica s proprietary PRS analysis software, the data showed that combining information on an individual s genetic risk of heart attack with their LDL level helps determine those at most risk from heart attack, including those potentially in need of treatment with statins or PCSK9 inhibitors.

Allelica s polygenic risk score data published in Circulation

Allelica s polygenic risk score data published in Circulation
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

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