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New Study More Clearly Links Vision Loss, Cognitive Declines

Scientists have long known that older adults with impaired vision face twice the risk of cognitive decline, the fifth-leading cause of disability among seniors. But the specific types of visual and mental keenness involved remain unclear. A new study in the journal JAMA Network Open brings them into sharper focus. The longitudinal study of 1,200 adults without dementia ages 60 to 94 looked at three types of vision loss and a full range of cognitive tests. Senior author Bonnielin Swenor of the Johns Hopkins Wilmer Eye Institute in Baltimore says that the work improves on previous studies, which often looked at only one measure of vision or lumped together different types of cognition.

Pandemic made kids eyesight worse, doctors say

The Eyes Are a Window Into Alzheimer s Disease, Suggests New Study

Read Time: While it has been said that the eyes are a window to the soul, a new study shows they could be a means for understanding diseases of the brain. According to new research by scientists at the UCSF Weill Institute for Neurosciences, retinal scans can detect key changes in blood vessels that may provide an early sign of Alzheimer s, while offering important insights into how one of the most common Alzheimer s risk genes contributes to the disease. The most prevalent genetic risk for Alzheimer s disease is a variant of the APOE gene, known as APOE4, said lead author Fanny Elahi, MD, PhD. We still don t fully understand how this variant increases risk of brain degeneration, we just know that it does, and that this risk is modified by sex, race, and lifestyle. Our research provides new insights into how APOE4 impacts blood vessels and may provide a path forward for early detection of neurodegenerative disease.

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