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Read Time: The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH) and the Princess Máxima Center for Pediatric Oncology, discovered that all neuroblastomas arise from a single type of embryonic cell called sympathoblasts. The study, published today (5 February 2021) in Science Advances, sought to understand why neuroblastomas range in severity, with some easy to treat and others having relatively low five-year survival rates. The fact that all neuroblastomas arise from sympathoblasts makes them an attractive drug target, because these cells exist only in the tumour after the child is born.

United kingdomKarin straathofSam behjatiJan molenaarCambridge university hospitalsWellcome sanger instituteGreat ormond street hospitalPediatric oncologyScience advancesHuman cell atlasஒன்றுபட்டது கிஂக்டம்ஜான் மொளேனார்கேம்பிரிட்ஜ் பல்கலைக்கழகம் மருத்துவமனைகள்வெல்கம் சாங்கர் நிறுவனம்நன்று ஆர்‌மஂட் தெரு மருத்துவமனைகுழந்தை புற்றுநோயியல்