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Radikalischer Angriff auf lebende Zellen
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Zellmarkierung: radikal präzise
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The use of mammalian cell surface display for rapid characterization of SARS-CoV-2 variants
A research group from the U.S. demonstrated the practicality of a spike display system in order to accelerate vaccine design, but also to swiftly appraise the effects of mutations in emerging strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the
bioRxiv preprint server.
SARS-CoV-2, the causative agent of the ongoing coronavirus disease (COVID-19), uses its spike glycoprotein to interact with angiotensin-converting enzyme 2 (ACE2) in order to fuse cell membrane and viral envelope. The key determinant of host tropism is the S1 subunit of the spike glycoprotein, composed of the receptor-binding domain (RBD) and N-terminal domain (NTD).
Scientists use a novel two-step method to track receptor proteins
The neurons in our nervous system talk to each other by sending and receiving chemical messages called neurotransmitters. This communication is facilitated by cell membrane proteins called receptors, which pick up neurotransmitters and relay them across cells. In a recent study published in
Nature Communications, scientists from Japan report their findings on the dynamics of receptors, which can enable understanding of the processes of memory formation and learning.
The regulation of receptor movement and localization within the neuron is important for synaptic plasticity, an important process in the central nervous system. A specific type of glutamate receptor, known as AMPA-type glutamate receptor (AMPAR), undergoes a constant cycle of trafficking , being cycled in and out of the neuronal membrane. A precise regulation of this trafficking process is associated with learning, memory formation, and developmen
Anti-Aging: Victoria Beckham schwört auf Omega-3-Kapseln
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