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IMAGE: CRISPR-sciATAC is a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene editing system. view more
Credit: Sanjana Lab of New York Genome Center and NYU
NEW YORK, NY (April 29, 2021) - In a new resource for the scientific community, published today in
Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. With this technology, they profile changes in genome organization and create a large-scale atlas of how loss of individual chromatin-altering enzymes impacts the human genome. The new method harnesses the programmability of the gene editing system CRISP
Five UConn faculty honored as Board of Trustees Distinguished Professors uconn.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from uconn.edu Daily Mail and Mail on Sunday newspapers.
Published: Apr 27, 2021
CAMBRIDGE, Mass. (BUSINESS WIRE) Repertoire Immune Medicines, a clinical-stage biotech company decoding the immune synapse to create novel immune therapies for cancer, immune disorders, infectious disease, and other serious diseases, today announced the company has elected neuroscience researcher and educator, Susan Hockfield, Ph.D., President Emerita of MIT, to its board of directors.
John Cox, Chief Executive Officer, Board of Directors, Repertoire Immune Medicines
“Dr. Hockfield is a tremendous addition to Repertoire Immune Medicines, as a scientist, organizational leader, and public servant,” said John Cox, CEO of Repertoire. “Our company is positioned at the frontier of immune medicines based on our ability to understand the drivers of cellular immunity. The breadth and depth of Dr. Hockfield’s experiences will help guide us along the way.”
Published: Apr 21, 2021
- Backed by leading healthcare investors including SV Health Investors -
Cambridge, UK, 20 April 2021 – Mestag Therapeutics (“Mestag”), a breakthrough inflammatory disease and immuno-oncology company, today announced its launch with $11 million seed financing from healthcare investors SV Health Investors and Johnson & Johnson Innovation – JJDC, Inc. (“JJDC”).
The Company’s mission is to develop new medicines for patients by targeting activated fibroblast populations and their role in influencing immune effector cells in disease. Powerful new technologies enable diseased tissues to be analyzed at a single-cell level, and this work has uncovered discrete fibroblast cell sub-populations shared across diseases, acting as “immune sentinels” in perpetuating, and progressing disease. Mestag is building a pipeline of first in class therapeutics to interrupt fibroblast-mediated effects on immune cells in inflammatory disease and immuno-oncolog