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New epigenetic regulatory mechanisms involved in multiple myeloma growth

An international team of researchers has analyzed the function of the histone demethylase KDM5A in multiple myeloma, one of the three major hematological cancers, and clarified the mechanism by which it promotes myeloma cell proliferation. They also developed a novel KDM5 inhibitor and showed that it inhibits cancer cell growth in a myeloma mouse model. The researchers expect that new therapies targeting KDM5A will be developed in the future.

United kingdomHiroto ohguchiKumamoto universityDana farber cancer instituteAssociate professor hiroto ohguchiBlood cancer discoveryLysine demethylaseMedicine healthPharmaceutical chemistryஒன்றுபட்டது கிஂக்டம்குமாமோடோ பல்கலைக்கழகம்டானா ஃபார்‌பர் புற்றுநோய் நிறுவனம்இரத்தம் புற்றுநோய் கண்டுபிடிப்புஉயிர் வேதியியல்

Diuretics Global Market Report 2021: COVID 19 Impact and Recovery to 2030

Share: New York, May 03, 2021 (GLOBE NEWSWIRE) Reportlinker.com announces the release of the report Diuretics Global Market Report 2021: COVID 19 Impact and Recovery to 2030 - https://www.reportlinker.com/p06067865/?utm source=GNW 91 billion in 2021 at a compound annual growth rate (CAGR) of 11%. The growth is mainly due to the companies rearranging their operations and recovering from the COVID-19 impact, which had earlier led to restrictive containment measures involving social distancing, remote working, and the closure of commercial activities that resulted in operational challenges. The market is expected to reach $1.18 billion in 2025 at a CAGR of 6.7%. The diuretic drugs market consists of sales of diuretic drugs and related services.Diuretic drugs help increase the flow of urine by reducing concentration of sodium and chloride in the body.

New yorkUnited statesUnited kingdomKumamoto universityInternational council for harmonizationNational kidney foundation incEuropean medicines agency regulationsEuropean medicines agencyMolecule envelop technology nanoparticles oral deliveryGlobal market reportCurrent good manufacturing practiceMolecule envelop technologyNanoparticles oralInternational councilGood manufacturing practiceQuality risk management

夜間頻尿からの解放の記事バックナンバー：からだケア：日経Gooday（グッデイ）

夜間頻尿からの解放の記事バックナンバー：からだケア：日経Gooday（グッデイ）
nikkei.co.jp - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nikkei.co.jp Daily Mail and Mail on Sunday newspapers.

Yoshida masakiKumamoto universityResearch centerProfessor nationalBook specialYoshida masaki sanCross hospital seniorMedical research centerDirector yoshida masaki sanAssociate professor nationalயோஷிடா மசாகிகுமாமோடோ பல்கலைக்கழகம்ஆராய்ச்சி மையம்நூல் சிறப்புமருத்துவ ஆராய்ச்சி மையம்

Could Peptide-Insulin Mixture Unlock the Prospect of Oral Diabetes Therapy?

Could Peptide-Insulin Mixture Unlock the Prospect of Oral Diabetes Therapy? April 28, 2021 The results of research by a team of scientists at Kumamoto University in Japan could feasibly provide the foundation for developing orally administered forms of insulin that would free diabetes patients from daily injections. The team’s studies first found that L-DNP peptide, a small intestine-permeable cyclic peptide originally used as an insulin additive to improve absorption into the small intestine, lowers blood glucose levels in mice. They then demonstrated that insulin can be administered orally by simply adding the D-form of the DNP peptide (D-DNP) to injectable insulin used in clinical practice. The results could represent the foundation for developing a more patient-friendly form of insulin therapy.

Shingo itoKumamoto universityMolecular pharmaceuticsஷிங்கோ இதோகுமாமோடோ பல்கலைக்கழகம்

Study may provide a basis for oral insulin development using DNP peptides

Study may provide a basis for oral insulin development using DNP peptides
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Shingo itoEmily hendersonKumamoto universityAssociate professorஷிங்கோ இதோஎமிலி ஹென்டர்சன்குமாமோடோ பல்கலைக்கழகம்இணை ப்ரொஃபெஸர்