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Antiviral drug thapsigargin effective against Covid, suggests study

Antiviral drug thapsigargin effective against Covid, suggests study February 04, 2021 Researchers believe it will help mitigate future outbreaks Researchers, including those from the University of Nottingham in the UK, have found an antiviral drug that is highly effective against the novel coronavirus. The researchers of the study believe that the administration of the drug thapsigargin will help in mitigating future outbreaks. They stated in their study that the plant-derived antiviral, in small doses, stimulates a highly effective host-centred antiviral innate immune response against three major types of human respiratory viruses. This includes Covid-19. According to the study, an antiviral of this type could potentially be made available for community use to control active infection and its spread.

Cancer drug found to be an effective antiviral against coronavirus

Cancer drug found to be an effective antiviral against coronavirus Joe Davies For Mailonline © Provided by Daily Mail MailOnline logo An experimental cancer drug derived from a poisonous plant could stop Covid-19 in its tracks, researchers believe.  Nottingham University academics claim thapsigargin should be effective against the coronavirus behind the pandemic and others that cause common colds. The drug, derived from the deadly carrot thapsia plant which is deadly to cattle and sheep and found in the western Mediterranean, is being trialled against prostate cancer.  But researchers testing the treatment on animals have found it may be able to stop infection with the SARS-CoV-2 coronavirus, which causes Covid. 

Ground-breaking drug discovery may prevent millions of Covid-19 hospital admissions

He called for funding and political backing for the new drug. “The whole beauty of TG is that if you can catch Covid early, everything is a lot simpler downstream, Prof Chang said. “You don t develop a serious illness and you stop the spread of Covid in its tracks.” Given that acute respiratory infections caused by different viruses are clinically indistinguishable at first, an effective broad-spectrum drug that can fight different virus types at the same time could significantly improve clinical management and control active infection and its spread. The research team discovered recently that TG can make cells highly resistant to infection by starting responses that disrupt the reproduction cycle of viruses, such as Covid-19, in several places at the same time.

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