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Scientists identify abnormal neural replay of memories in people with schizophrenia

Scientists identify abnormal neural replay of memories in people with schizophrenia Neuroscientists at UCL have, for the first time, identified abnormalities in the way memories are replayed in the brains of people with schizophrenia; researchers say the pathbreaking study provides an entirely new basis for explaining many of the condition s core symptoms. Schizophrenia is a serious and debilitating mental disorder characterised by episodes of psychosis. Symptoms include hallucinations (typically hearing voices), delusions, and disorganised thinking. It affects around 20 million people globally, though the exact cause is unknown. In the study, published in the journal Cell, researchers used state-of-the-art brain imaging, known as magnetoencephalography (MEG), along with machine learning tools, to measure and assess neural activity corresponding to inner states of mind during rest periods when the brain is consolidating its prior experiences.

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