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BOSTON - Reports of possible allergic reactions to the COVID-19 vaccines produced by Pfizer-BioNTech and Moderna, both recently approved for emergency use by the U.S. Food and Drug Administration (FDA), have raised public concern. A team of experts led by allergists at Massachusetts General Hospital (MGH) has now examined all relevant information to offer reassurance that the vaccines can be administered safely even to people with food or medication allergies. The group s review is published in the
In response to accounts of potential allergic reactions in some people following COVID-19 vaccination in the United Kingdom, that country s medical regulatory agency advised that individuals with a history of anaphylaxis to a medicine or food should avoid COVID-19 vaccination. After closer review of the data related to allergic reactions, however, the FDA recommended that the vaccines be withheld only from individuals with a history of severe allergic reactions to any component
December 27, 2020/Charles Betzler/Last Updated December 27, 2020
Doctors and scientists are investigating the reason behind several severe allergic reactions to COVID-19 vaccines. Thus far just over 1 million doses of the Pfizer and Moderna vaccines have been administered. Anaphylaxis was not reported during clinical trials for either the Pfizer-BioNTech or Moderna versions.
According to The Centers for Disease Control and Prevention (CDC), as of December 19, six people who received the Pfizer vaccine in the United States developed anaphylaxis, which is an acute allergic reaction that can be life-threatening without medical intervention. On Friday, December 24, a doctor in Boston with a shellfish allergy, who received the Moderna vaccine, suffered an anaphylactic reaction immediately after being vaccinated. There have been two anaphylactic reactions in the U.K. Although anaphylactic reactions are a possibility with any vaccine, they are exceedingly rare, with a frequency of 1 e
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