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Rho to Coordinate Study Sponsored by NIAID to Assess Systemic Allergic Reactions to Pfizer and Moderna COVID-19 Vaccines

Rho to Coordinate Study Sponsored by NIAID to Assess Systemic Allergic Reactions to Pfizer and Moderna COVID-19 Vaccines
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Scientists home in on potential cause of rare COVID-19 vaccine allergic reactions

Scientists are homing in on the potential cause of allergic reactions to the Pfizer-BioNTech COVID-19 vaccine.The United States Centers for Disease Control and Prevention has recorded six severe allergic reactions (all of which were treated successfully) out of the 272,001 doses administered through Dec. 19, and the compound polyethylene glycol, known as PEG, has become a leading suspect in the cases, The Wall Street Journal reports. While still speculative at this point — allergies to PEG are rare and the reactions may have been to something else, per the Journal — PEG is found in other drugs, cosmetics, and food and is known to trigger anaphylaxis on rare occasions, though not all forms of the compound are "equal" in terms of allergic potential.Part of the challenge of pinpointing PEG as the likely catalyst for the reactions is that the compound in the vaccines "is different than what has been previously associated with allergic reactions," James Bak

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