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 E-Mail IMAGE: EGCG maintains neuronal cell cytoskeleton integrity. Methyl glyoxal treatment leads to glycation of actin and microtubules leading to hampered growth of neuritic extensions and microtubule organization. Microtubule stabilization by +TIP. view more  Credit: Correspondence to - Subashchandrabose Chinnathambi - s.chinnathambi@ncl.res.in Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network which reported that the chemical modulators of Tau PTMs, such as kinase inhibitors and antibody-based therapeutics, have been developed, but natural compounds, as modulators of Tau PTMs are not much explored. These authors applied biophysical and biochemical techniques like fluorescence kinetics, oligomerization analysis and transmission electron microscopy to investigate the impact of EGCG on Tau glycation

Subashchandrabose chinnathambiInnovative researchChinnathambi research teamImpact journalsResearch outputAcademy of scientificChemical laboratoryTau post translationalNational chemical laboratoryபுதுமையானது ஆராய்ச்சிஒலி கிளவுட்தாக்கம் பத்திரிகைகள்ஆராய்ச்சி ஔட்‌புட்கலைக்கழகம் ஆஃப் அறிவியல்இரசாயன ஆய்வகம்தேசிய இரசாயன ஆய்வகம்