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Alcohol may have immediate effect on atrial fibrillation risk, events

Alcohol appears to have an immediate or near-immediate effect on heart rhythm, significantly increasing the chance that an episode of atrial fibrillation (AFib) will occur, according to new data presented at the American College of Cardiology s 70th Annual Scientific Session.

Brigham-led clinical trials take center stage at the American College of Cardiology

Top experts from Brigham and Women s Hospital presented outcomes from some of the most-anticipated clinical trials in cardiology at the virtual American College of Cardiology s 70th Annual Scientific Session. In four Late-Breaking Clinical Trial presentations, Brigham cardiologists shared their latest findings on strategies to prevent future cardiovascular events in at-risk patient populations, results of a randomized clinical trial of a statin drug among patients critically ill with COVID-19, and more.

Omecamtiv Mecarbil brings greater benefits for severe heart failure

The experimental heart failure drug omecamtiv mecarbil reduced heart failure hospitalizations by a greater margin among patients with more severely reduced ejection fraction, a measure indicating severe impairment in the heart s pumping ability, compared with those who had moderately reduced ejection fraction, according to research presented at the American College of Cardiology s 70th Annual Scientific Session.

Pirfenidone reduces scar tissue in patients with heart failure

Patients with heart failure with preserved ejection fraction who took the antifibrotic drug pirfenidone saw a significant reduction in a marker of heart muscle scarring compared with patients who received a placebo, based on findings from an early-phase trial presented at the American College of Cardiology s 70th Annual Scientific Session.

New cardiac rehabilitation intervention improves quality of life in hospitalized heart failure patients

An innovative cardiac rehabilitation intervention started earlier and more custom-tailored to the individual improved physical function, frailty, quality-of-life, and depression in hospitalized heart failure patients, compared to traditional rehabilitation programs.

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