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Cytokinetics Inc (CYTK) Q1 2021 Earnings Call Transcript

Operator Good afternoon, and welcome, ladies and gentlemen, to Cytokinetics First Quarter 2021 Conference Call. At this time, I would like to inform you that this call is being recorded and that all participants are in a listen-only mode. At the company s request, we will open the call for questions-and-answers after the presentation. I will now like to turn the call over to Diane Weiser, Cytokinetics Senior Vice President of Corporate Communications and Investor Relations. Please go ahead. Diane Weiser Senior Vice President of Corporate Communications & Investor Relations Good afternoon, and thanks for joining us on the call today. Robert Blum, our President and Chief Executive Officer, will kick off the call with an overview of the quarter and recent developments. Then Fady Malik, our EVP of Research and Development, will provide an update on omecamtiv mecarbil, including progress following a recent meeting with FDA and what to expect from upcoming analyses from GALACTIC-H

High-risk, disadvantaged groups face barriers to preventing spread of COVID-19

 E-Mail Social factors such as education, financial stability, food security and the neighborhood where someone resides were strongly correlated with whether or not individuals with heart disease adopted measures to prevent the spread of COVID-19, including wearing masks and working from home, according to a study presented at the American College of Cardiology s 70th Annual Scientific Session. The researchers say the findings draw attention to longstanding challenges related to social determinants of health. Unless we look at COVID-19 through the lens of social determinants of health, we may not optimize our yield from interventions, and we might not be reaching the group of individuals who need these interventions the most, said Kobina Hagan, MD, a postdoctoral fellow at Houston Methodist Research Institute and the study s lead author.

Men with chest pain receive faster, more medical attention than women

 E-Mail Among younger adults visiting the emergency department for chest pain, women may be getting the short end of the stick. Compared with men of similar age, women were triaged less urgently, waited longer to be seen, and were less likely to undergo basic tests or be hospitalized or admitted for observation to diagnose a heart attack, according to new research being presented at the American College of Cardiology s 70th Annual Scientific Session. The study is the first to examine emergency room management of chest pain specifically among younger adults (age 18-55 years). Heart disease is the leading cause of death in women and is becoming more common in younger adults. About one-third of women who were hospitalized for a heart attack in the past two decades were under the age of 55, a proportion that has grown in recent years.

Mental health may play big role in recovery after a heart attack

 E-Mail Young and middle-aged adults who reported severe psychological distress such as depression or anxiety after suffering a heart attack were more than twice as likely to suffer a second cardiac event within five years compared with those experiencing only mild distress, according to a study presented at the American College of Cardiology s 70th Annual Scientific Session. The study is the first to comprehensively assess how mental health influences the outlook for younger heart attack survivors, according to the researchers. The researchers also tracked inflammatory markers that appear to have a role in increasing cardiovascular risk among people experiencing distress. The findings align with previous studies focusing on older adults, bolstering the evidence for mental health as an integral part of a person s recovery after a heart attack.

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