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Den Kreislauf der Opioidabhängigkeit durchbrechen: Alar präsentiert positive Zwischenergebnisse der langwirksamen Buprenorphin-Injektionslösung (ALA-1000) bei opioidabhängigen Patienten
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Rompre le cycle de la dépendance aux opioïdes : Alar présente les résultats intermédiaires positifs de la buprénorphine injectable à action prolongée (ALA-1000) chez les patients dépendants aux opioïdes
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10 marzo 2021 09:05
Fonte: Adnkronos
#chimica-e-farmacia
TAICHUNG, March 10, 2021 /PRNewswire/ Alar Pharmaceuticals Inc. (TWSE:6785), a clinical-stage biopharmaceutical company focused on developing long-acting injectables (LAIs) for central nervous system disorders, announces positive interim results from the single-ascending-dose study of ALA-1000. A 3-month buprenorphine released injectable designed to be dosed subcutaneously for treating opioid use disorder (OUD).
The Buprenorphine release from the ALA-1000 single injection lasts over 12 weeks with effective concentrations, showing low initial burst without dose dumping effect and good safety and tolerability, including local skin irritation and injection pain severity.
Opioid dependency: A world health issue
The world-wide opioid epidemic is a documented public health crisis. Treatments for opioid abuse currently rely on Buprenorphine, Methadone, and Naltrexone as Medication-assisted treatment (MAT). However, patients n