E. Coli Engineered to Diagnose Inflammatory Bowel Disease
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May 17, 2021
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Rice University researchers say they have engineered a bacterium with the necessary capabilities for diagnosing a human disease. The engineered strain of the gut bacteria
E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel diseases like colitis, ileitis, and Crohn’s disease, according to the scientists.
Researchers at the University of Colorado (CU) School of Medicine used the Rice-created organism in a mouse model of Crohn’s disease to show acidosis activates a signature set of genes. The corresponding genetic signature in humans has previously been observed during active inflammation in Crohn’s disease patients. The study (“Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation”) is availa
Rice University bioengineers are fabricating and testing tunable electrospun scaffolds completely derived from decellularized skeletal muscle to promote the regeneration of injured skeletal muscle.Aligned myotubes formed on electrospun extracellular
Researchers develop stimulators that could aid spinal cord, heart therapies ANI | Updated: May 11, 2021 11:27 IST
Houston (Texas) [US], May 11 (ANI): Engineers have developed a new version of their wireless implant that allows for multiple stimulators to be programmed and magnetically powered from a single transmitter outside the body. The implants could be used to treat spinal cord injuries or as pacemakers.
Now, for therapies that require multiple, coordinated stimulation implants, their timing has come as well.
Rice University engineers who developed implants for electrical stimulation in patients with spinal cord injuries have advanced their technique to power and program multisite bio stimulators from a single transmitter.
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IMAGE: A new version of wireless implants developed at Rice University allows for multiple stimulators, as seen here, to be programmed and magnetically powered from a single transmitter outside the body.. view more
Credit: Secure and Intelligent Micro-Systems Lab/Rice University
HOUSTON - (May 10, 2021) - Implants that require a steady source of power but don t need wires are an idea whose time has come.
Now, for therapies that require multiple, coordinated stimulation implants, their timing has come as well.
Rice University engineers who developed implants for electrical stimulation in patients with spinal cord injuries have advanced their technique to power and program multisite biostimulators from a single transmitter.
Researchers have shown wearable devices that continuously monitor blood sugar provide new insights into the progression of Type 2 diabetes among at-risk Hispanic/Latino adults.