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Neoadjuvant Opdivo Plus Chemotherapy Significantly Improves Pathologic Complete Response in Patients with Resectable Non-Small Cell Lung Cancer in Phase 3 CheckMate -816 Trial

Nearly a quarter of patients who received Opdivo plus chemotherapy showed no evidence of cancer cells in tissue removed during surgery vs. 2.2% of patients who received chemotherapy alone Opdivo- based therapies have now demonstrated positive results in Phase 3 trials in earlier stages of four different types of cancer: non-small cell lung cancer, esophagealgastroesophageal junction cancer, bladder cancer and … Nearly a quarter of patients who received Opdivo plus chemotherapy showed no evidence of cancer cells in tissue removed during surgery vs. 2.2% of patients who received chemotherapy alone Opdivo- based therapies have now demonstrated positive results in Phase 3 trials in earlier stages of four different types of cancer: non-small cell lung cancer, esophageal/gastroesophageal junction cancer, bladder cancer and melanoma

United statesSouth koreaAbderrahim oukessouNina goworekBristol myers squibbInstitut curieNicolas girardCompany opdivoBristol myers squibb companyExchange commissionAmerican association for cancer researchAmerican association for cancer research annual meetingOno pharmaceutical coEuropean unionClinical trials plenary sessionAmerican association

Mersana Therapeutics Presents Preclinical Data Highlighting Potential of XMT-2056 and XMT-1660 in Three Posters at Virtual 2021 AACR Annual Meeting

Mersana Therapeutics Presents Preclinical Data Highlighting Potential of XMT-2056 and XMT-1660 in Three Posters at Virtual 2021 AACR Annual Meeting April 10, 2021 09:00 ET | Source: Mersana Therapeutics, Inc. Mersana Therapeutics, Inc. Cambridge, Massachusetts, UNITED STATES CAMBRIDGE, Mass., April 10, 2021 (GLOBE NEWSWIRE) Mersana Therapeutics, Inc. (NASDAQ:MRSN), a clinical-stage biopharmaceutical company focused on discovering and developing a pipeline of antibody-drug conjugates (ADCs) targeting cancers in areas of high unmet medical need, today presented preclinical data from XMT-1660, a B7-H4-targeted Dolasynthen antibody-drug conjugate (ADC), and XMT-2056, an Immunosynthen-based STING-agonist ADC at the Virtual 2021 American Association for Cancer Research Annual Meeting being held from April 10-15th.

United kingdomUnited statesTimothyb lowingerAnna protopapasAmerican association for cancer research annual meetingMersana therapeutics incAmerican associationCancer research annual meetingChief scienceTechnology officerChief executive officerImmunomodulatory agentsஒன்றுபட்டது கிஂக்டம்ஒன்றுபட்டது மாநிலங்களில்அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி ஆண்டு சந்தித்தல்அமெரிக்கன் சங்கம்

New CAR T approach minimizes resistance, helps avoid relapse in non-Hodgkin s B-cell lymphoma

New CAR T approach minimizes resistance, helps avoid relapse in non-Hodgkin s B-cell lymphoma
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United statesSanaz ghafouriSarah larsonYvonne chenJean kaplanStem cell researchParker institute of cancer immunotherapyAmerican association for cancer research annual meetingDavid geffen school of medicineJonsson comprehensive cancer center tumor immunology programJonsson comprehensive cancer centerEdythe broad centerComprehensive cancer centerAmerican associationCancer research annual meetingDavid geffen school

HOOKIPA announces positive preliminary Phase 1 immunogenicity data for its immunotherapy

HOOKIPA announces positive preliminary Phase 1 immunogenicity data for its immunotherapy
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United statesMatt beckNina waibelImmunospot elispotDmitriy zamarinJoern aldagExchange commissionAmerican association for cancer research annual meetingPharma incTranslational researchGilead sciences incHuman papillomavirusAmerican associationCancer research annualChief executive officerEnzyme linked immunospot

Here s Why Shares of Affimed Skyrocketed Today

Shares of drugmaker Affimed (NASDAQ:AFMD) are up 19% at 2:06 p.m. EDT after the company disclosed positive data from an early-stage clinical trial of its innate cell engager AFM13 in patients with Hodgkin s lymphoma. So what The data release only included results from the first four patients in the study, but they were impressive nonetheless. All four patients responded to the therapy, which included giving the patients immune cells called natural killer (NK) cells and AFM13 that attracts the NK cells to the tumor cells. Two patients had a complete response, while the other two had a partial response. Adding to the impressiveness, these patients had already failed between four and 14 different lines of therapy before being given the NK cells plus AFM13.

United statesAmerican association for cancer research annual meetingRoche holdingAmerican associationCancer research annualஒன்றுபட்டது மாநிலங்களில்அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி ஆண்டு சந்தித்தல்ரோச் வைத்திருத்தல்அமெரிக்கன் சங்கம்புற்றுநோய் ஆராய்ச்சி ஆண்டு