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KRAZATI (adagrasib) Demonstrated Statistically Significant Improvement in Progression-Free Survival in Patients with Pretreated Locally Advanced or Metastatic KRASG12C-Mutated Non-Small Cell Lung Cancer

First presentation of data from Phase 3 KRYSTAL-12 study showed statistically significant and clinically meaningful improvement in progression-free survival with KRAZATI compared to standard of care.

United statesBristol myers squibbTony mokAbderrahim oukessouExchange commissionDepartment of clinical oncologyAmerican society of clinical oncologyMirati therapeutics incChinese university of hong kong cu medicineDrug administrationBlinded independent central reviewClinical oncologyAnnual meetingChinese universityHong kongBristol myers

Bristol Myers Squibb shares positive phase 3 results for Krazati in non-small cell lung cancer

Bristol Myers Squibb shares positive phase 3 results for Krazati in non-small cell lung cancer
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Bristol myers squibbAbderrahim oukessouRegulatory agencyWorld cancer research fund internationalEuropean commissionDrug administrationMyers squibbWorld cancer research fund

Adagrasib Meets Primary Endpoint Among Individuals with KRAS G12C-Mutated Locally Advanced or Metastatic NSCLC

The positive results in both progression-free survival and overall response rate were endorsed in a confirmatory study.

Bristol myers squibbAbderrahim oukessouPrescription drug user fee actBlinded independent central reviewTrial evaluatingMeets primary endpointProgression free survivalMutated locally advancedMetastatic non small cellBristol myers

Adagrasib Improves PFS, ORR in Previously Treated KRAS G12C–Mutant NSCLC

Adagrasib improved progression-free survival and objective response rates vs docetaxel in pretreated KRAS G12C–mutant non–small cell lung cancer.

United statesAbderrahim oukessouBristol myers squibbMirati therapeutics incEuropean commissionDrug administrationRegulatory agencyMyers squibbKras g12cNon small cell lung cancerLung cancer

Bristol Myers Squibb Announces Pivotal KRYSTAL-12 Confirmatory Trial Evaluating KRAZATI (adagrasib) Meets Primary Endpoint of Progression-Free Survival for Patients with Pretreated KRASG12C-Mutated Locally Advanced or Metastatic Non-Small Cell Lung…

PRINCETON, N.J. (BUSINESS WIRE) Mar 28, 2024

United statesBristol myers squibbAbderrahim oukessouBristol myers squibbmediaExchange commissionRegulatory agencyEuropean commissionTrial evaluatingMeets primary endpointProgression free survivalMutated locally advancedMetastatic non small cell lungMyers squibbBlinded independent central reviewBristol myersPrescription drug user fee act