Selective immunotoxins may help treat liver fibrosis
Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.
So we thought…what if we take immunotoxins and try to get them to kill collagen-producing cells in the liver. If these antibodies carrying toxic molecules can find and bind the cells, the cells will eat up the gift and die.
Tatiana Kisseleva, MD, PhD, Team Lead, Associate Professor of Surgery, UC San Diego School of Medicine
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