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Spleen-to-liver signals control systemic inflammation, rat study reveals -- Health & Wellness -- Sott net

© NATALLIA YATSKOVA/ISTOCK.COM, In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger. Contrary to established dogma, the spleen is not the principal source of the pro-inflammatory cytokine called tumor necrosis factor (TNF), which drives the sort of system-wide inflammation seen in sepsis. A paper in Science Signaling last week (April 20) reports that the liver and lungs of rats produce more TNF than the spleen does, but the spleen remains the master regulator, of the liver at least, instructing the nearby organ, via lipid signals, on how much TNF to make.

Northwell Commits $1 3M to Fund Innovative Employee Ideas

Northwell Commits $1 3M to Fund Innovative Employee Ideas
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Northwell invests $1 3M in innovative employee ideas

Get our free LIBN e-alerts & breaking news notifications! Dr. Jared Huston, Northwell Health President & CEO Michael Dowling, Anne Marie McDonough and Alina Segal, winners of the 2021 Innovation Challenge. Credit Northwell Health Northwell invests $1.3M in innovative employee ideas By: Adina Genn May 6, 2021 Comments Off on Northwell invests $1.3M in innovative employee ideas A 3D-device to detect ulcers. And a new way to treat bleeding disorders. These are just some of the innovations coming out of Northwell Health’s 2021 Innovative Challenge, aimed at helping to improve healthcare. Northwell Health is investing $1.3 million for research and development of projects, established by its employees, that could be healthcare game-changers.

Northwell Commits $1 3M to Fund Innovative Employee Ideas

Northwell Commits $1.3M to Fund Innovative Employee Ideas Search jobs Northwell Commits $1.3M to Fund Innovative Employee Ideas NEW HYDE PARK, N.Y. (BUSINESS WIRE) Northwell Health has awarded $1.3 million toward the research and development of four employee-driven projects that have the potential to transform the future of health care. After a one-year hiatus, the health system renewed its annual ideas showcase – known as the 2021 Innovation Challenge – and came away with two potentially transformative projects: a 3D imaging device to identify tissue pressure injuries early and a spleen stimulator to treat bleeding. Northwell tapped into the marketplace of ideas by giving employees an opportunity to receive funding through the internal competition. Now in its fifth year, the 2021 Innovation Challenge drew 74 submissions in two categories, which were winnowed down to seven finalists. Two winners along with two runners up were announced on May 3.

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