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An M Sc computer science program in RUNI, focusing on machine learning

An exclusive program that addresses both deep foundations as well as practical skills, in the spirit of Reichman university

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Accurate evaluation of CRISPR genome editing

E-Mail CRISPR technology allows researchers to edit genomes by altering DNA sequences and by thus modifying gene function. Its many potential applications include correcting genetic defects, treating and preventing the spread of diseases and improving crops. Genome editing tools, such as the CRISPR-Cas9 technology, can be engineered to make extremely well-defined alterations to the intended target on a chromosome where a particular gene or functional element is located. However, one potential complication is that CRISPR editing may lead to other, unintended, genomic changes. These are known as off-target activity. When targeting several different sites in the genome off target activity can lead to translocations, unusual rearrangement of chromosomes, as well as to other unintended genomic modifications.

Daniel allenGarrettr rettigAnavy technionMark behlkeIdo amitAyal hendelChihong choiNimrod ben haimMatthews mcneilZohar yakhiniGavin kurganJurgenson technionOrtal iancuHendel labNature communicationsYakhini research group

Researchers develop tool to accurately evaluate CRISPR genome editing

Researchers develop tool to accurately evaluate CRISPR genome editing ANI | Updated: May 24, 2021 16:31 IST Washington [US], May 24 (ANI): During a recent study, researchers from the IDC Herzliya and Bar-Ilan University developed a novel software tool to quantify potential CRISPR-induced errors. CRISPR is the technology that allows researchers to edit genomes by altering DNA sequences and by thus modifying gene function. The study was published in the journal Nature Communications. The many potential applications of CRISPR include correcting genetic defects, treating and preventing the spread of diseases, and improving crops. Genome editing tools, such as the CRISPR-Cas9 technology, can be engineered to make extremely well-defined alterations to the intended target on a chromosome where a particular gene or functional element is located.

United statesAyal hendelZohar yakhiniNature communicationsIlan universityInterdisciplinary center herzliyaEverard goodman faculty of life sciencesIlan university minaBar ilan universityNext generation sequencingEverard goodman facultyArazi schoolComputer scienceInterdisciplinary centerProf yakhiniSoftware tool

New Israeli tech gives accuracy boost to microscopic scissors for DNA editing

The CRISPR technique snips DNA, but what if it cuts the wrong location in the genome without scientists realizing? Software innovation provides alerts

United statesTel avivAyal hendelZohar yakhiniNature communicationsTel aviv university drDrug administrationIsrael institute of technologyBar ilanTel aviv universityTechnion israel instituteஒன்றுபட்டது மாநிலங்களில்தொலைபேசி அவிவ்அயல் ஹெண்டல்இயற்கை தகவல்தொடர்புகள்தொலைபேசி அவிவ் பல்கலைக்கழகம் டாக்டர்

IDC Herzliya, Bar-Ilan, Develop Software to Help Measure DNA Sequencing Errors | The Jewish Press - JewishPress com | Jewish Press News Desk | 13 Sivan 5781 – May 24, 2021

IDC Herzliya, Bar-Ilan, Develop Software to Help Measure DNA Sequencing Errors | The Jewish Press - JewishPress com | Jewish Press News Desk | 13 Sivan 5781 – May 24, 2021
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Tel avivAyal hendelZohar yakhiniNature communicationsIlan universityInterdisciplinary center herzliyaEverard goodman faculty of life sciencesIlan university minaPhoto creditBar ilan universityNext generation sequencingEverard goodman facultyArazi schoolComputer scienceInterdisciplinary centerProf yakhini