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Makhosandile Mngewu, 53, and his brother Dr Thandukwazi Mngewu, 52, both died from Covid-19 on Sunday.
The two had attended a funeral service of their elder sister a few weeks ago, where they reportedly contracted the virus.
Eastern Cape Premier Oscar Mabuyane has called funerals a big problem and super-spreaders of Covid-19 virus.
An Eastern Cape deputy principal and his brother died on the same day from Covid-19-related issues after attending their sister s funeral a few weeks ago.
Nyanga High School deputy principal Makhosandile Mngewu, 53, and his brother Dr Thandukwazi Mngewu, 52, both died on Sunday, after attending a funeral service of their elder sister a few weeks ago, according to the Mngewu family.