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IMAGE: The mitoribosome is attached to its membrane adaptor as it synthesises a bioenergetic protein (glow yellow). view more
Credit: Dan W. Nowakowski and Alexey Amunts
Scientists uncover for the first time how the body s energy makers are made using Cryo-Electron Microscopy (cryo-EM) at eBIC within Diamond which is based in Oxfordshire.
A new paper published in
Science today (19 February 2021) by an international team of researchers reports an insight into the molecular mechanism of membrane-tethered protein synthesis in mitochondria. This is a fundamental new understanding of how the human mitoribosome functions and could explain how it is affected by mutations and deregulation that lead to disorders such as deafness and diseases including cancer development.