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<p>A team of researchers based at the <a href="https://www.pharmacy.utoronto.ca/">University of Toronto&rsquo;s (U of T) Leslie Dan Faculty of Pharmacy</a> has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues. The team also showed that mRNA delivered by the lipid nanoparticles investigated in their study triggered potent cellular-level immune responses as a proof-of-concept melanoma cancer vaccine.</p>

United statesKate richardsYue xuJingan chenBowen liT leslie danMethod of researchInstitute of biomedical engineeringUniversity of torontoProceedings of the national academy sciencesLeslie dan facultyNational academyGairdner early career investigatorBiomedical engineeringDan faculty